Chemistry

Substitutive structure of a tryptamine molecule


DMT, or N,N-dimethyltryptamine, is a member of a family of organic compounds known as tryptamines. Tryptamines share a core structure consisting of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 

DMT contains two methyl groups (CH3-) bound to the terminal amine RN at the end of this chain.

It has many homologs and analogs from base tryptamines like MET and DPT, to four and five position substituted variants such as 4-PO-DMT (psilocybin), 4-AcO-DMT (psilacetin), 5-HO-DMT (bufotenin), and 5-MeO-DMT.

It is a white, pungent-smelling, crystalline solid. It is insoluble in water, but soluble in organic solvents and aqueous acids.

DMT is commonly handled and stored as a fumarate, as other DMT acid salts are extremely hygroscopic and will not readily crystallize. Its freebase form, although less stable than DMT fumarate, is favored by recreational users choosing to vaporize the chemical as it has a lower boiling point.

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